Published 2005 | Version v1
Journal article Metadata-only

Assessment by cytogenetic analysis of the radioprotection properties of propolis extract

Creators

  • 1. Servicio de Proteccion Radiologica, Hospital la Fe, Av/Campanar no. 21, Valencia 46009 (Spain)
  • 2. Dieteticos Intersa, Plaza Drive Seres no. 13, Torreserona, Lleida 25131 (Spain)
  • 3. Servicio de Dosimetria Biologica, Departamentos de Biologia Animal, Universitat Autonoma de Barcelona, Barcelona (Spain)
  • 4. Departamento de Ingenieria Quimica y Nuclear, UPV, Camino de Vera s/n, Valencia (Spain)
  • 5. Seccion de Radiofisica, Servicio de Radioterapia, Hospital la Fe, Valencia (Spain)

Description

Propolis obtained from honeybee hives has been used in folk medicine as an anti-inflammatory, anti-carcinogenic or immunomodulatory agent. In animal studies, the radioprotector effect of propolis has been attributed to its free-radical scavenging properties. The present study was carried out to show the protective properties of propolis extract against DNA damage induced by gamma irradiation. The evaluation of the radioprotective effect of propolis has been carried out by the analysis of chromosome aberration induction after several doses of gamma rays. The results of an analysis in the presence of ethanol extract of propolis (EEP) were compared with the dose-effect calibration curve for gamma-rays by analysis of chromosome aberrations without propolis, a decrease in the radiation-induced chromosome aberrations has been observed to be higher than 50% for all the doses. (authors)

Availability note (English)

Available from doi: http://dx.doi.org/10.1093/rpd/nci026

Additional details

Identifiers

DOI
10.1093/rpd/nci026;

Publishing Information

Journal Title
Radiation Protection Dosimetry
Journal Volume
115
Journal Issue
1-4
Journal Page Range
p. 461-464
ISSN
0144-8420

Conference

Title
10. International Conference on Radiation Shielding, and 13. ANS Topical Meeting on Radiation Protection and Shielding - ICRS-10/RPS 2004
Dates
9-14 May 2004
Place
Funchal, Madeira Island (Portugal)

INIS

Country of Publication
United Kingdom
Country of Input or Organization
France
INIS RN
44036017
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S61: RADIATION PROTECTION AND DOSIMETRY;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BEES; CALIBRATION; CHROMOSOMAL ABERRATIONS; CHROMOSOMES; DNA; DNA DAMAGES; DOSE-RESPONSE RELATIONSHIPS; DOSIMETRY; ETHANOL; GAMMA RADIATION; LYMPHOCYTES; RADIATION DOSES; RADIATION INJURIES
Descriptors DEC
ALCOHOLS; ANIMAL CELLS; ANIMALS; ARTHROPODS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BIOLOGICAL RADIATION EFFECTS; BLOOD; BLOOD CELLS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; DISEASES; DOSES; ELECTROMAGNETIC RADIATION; HYDROXY COMPOUNDS; HYMENOPTERA; INJURIES; INSECTS; INVERTEBRATES; IONIZING RADIATIONS; LEUKOCYTES; MATERIALS; MUTATIONS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; RADIATION EFFECTS; RADIATIONS; SOMATIC CELLS

Optional Information

Notes
16 refs