Depressed eruption rate of the rat maxillary incisor in a drug-induced uncompensated hemolytic state model
Description
Female rats weighing about 180 g were separated into two groups. One group (A) received phenylhydrazine (PHZ) every other day during three weeks (for induction of an uncompensated hemolytic state), while the control group (C) received saline. The evidence for the establishment of the uncompensated hemolytic state was obtained by hematocrit value, reticulocyte count, and red-cell-volume-59Fe uptake. Body-weight gain (which is a measure of overall body growth rate), body-length gain (which is a measure of longitudinal skeletal growth rate), food intake, and maxillary incisor eruption rate (ER) were significantly depressed in rats of group A during the PHZ-injection period, in relation to rats of group C. These results indicate that anemia and/or associated factors depress ER, along with body growth and skeletal growth
Additional details
Publishing Information
- Journal Title
- Journal of Dental Research
- Journal Volume
- 69
- Journal Issue
- 3
- Series
- J. Dent. Res.
- Journal Page Range
- 906-908
- ISSN
- 0022-0345
- CODEN
- JDREA
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 21067398
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Descriptors DEI
- ANEMIAS; ANIMAL GROWTH; BIOLOGICAL EFFECTS; BIOLOGICAL MODELS; BLOOD COUNT; CELL DIFFERENTIATION; ERYTHROCYTES; HEMOLYSIS; HYDRAZINE; INHIBITION; IRON 59; RATS; TEETH; TRACER TECHNIQUES; WEIGHT
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CHEMICAL REACTIONS; DAYS LIVING RADIOISOTOPES; DECOMPOSITION; DIGESTIVE SYSTEM; DISEASES; EVEN-ODD NUCLEI; GROWTH; HEMIC DISEASES; INTERMEDIATE MASS NUCLEI; IRON ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MAMMALS; MATERIALS; NUCLEI; ORAL CAVITY; RADIOISOTOPES; RODENTS; SYMPTOMS; VERTEBRATES