Published June 1982
| Version v1
Journal article
Radiation response of the canine cardiovascular system
Description
The hearts of dogs were irradiated with 60Co γ rays. The dose required to produce pericardial effusion in 50% of the dogs by 180 days (PED50/180) was 1220 rad. For cardiac tamponade, the CTD 50/180 was 1500 rad. Morphometric analyses of the hearts showed decreased capillary volume and increased fibrosis as radiation dose increased. The pericardial thickness increased with increased radiation dose. The slopes of the dose response for these parameters were similar as determined by linear regression of the parameter versus radiation dose
Additional details
Publishing Information
- Journal Title
- Radiat. Res.
- Journal Volume
- 90
- Journal Issue
- 3
- Series
- Radiat. Res.
- Journal Page Range
- 489-500
- ISSN
- 0033-7587
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 14731751
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; COBALT 60; DOGS; DOSE-RESPONSE RELATIONSHIPS; FIBROSIS; HEART; MORPHOLOGICAL CHANGES; RADIATION DOSES; RADIOSENSITIVITY
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BODY; CARDIOVASCULAR SYSTEM; COBALT ISOTOPES; DISEASES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANS; PATHOLOGICAL CHANGES; RADIATION EFFECTS; RADIOISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES