Published January 1980
| Version v1
Journal article
Early release of surfactant following lung irradiation of alveolar type II cells
- 1. Univ. of Rochester Cancer Center, NY
Description
At 1 hour, 24 hours, and 1 week following irradiation, studies utilizing LAF 1/J mouse lung showed increase of disaturated alveolar phosphatidylcholine (PC) by radiolabelling and alveolar lavage, thus indicating PC as a nearly immediate post-irradiation biomarker. A corresponding decrease of PC in lung tissue following alveolar lavage correlated with an early decrease of lamellar bodies in type II pneumocytes after irrdiation
Additional details
Publishing Information
- Journal Title
- Int. J. Radiat. Oncol., Biol. Phys.
- Journal Volume
- 6
- Journal Issue
- 1
- Series
- Int. J. Radiat. Oncol., Biol. Phys.
- Journal Page Range
- 75-77
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 11558473
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Numerical Data
- Descriptors DEI
- BIOLOGICAL INDICATORS; CESIUM 137; CHOLINE; CHROMATOGRAPHY; EARLY RADIATION EFFECTS; EXPERIMENTAL DATA; GAMMA RADIATION; LAVAGE; LUNGS; MICE; PHOSPHOLIPIDS; RESPIRATORY TRACT CELLS; SURFACTANTS; TABLES; TRACER TECHNIQUES; TRITIUM COMPOUNDS
- Descriptors DEC
- ALCOHOLS; AMINES; ANIMAL CELLS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; CESIUM ISOTOPES; DATA; DATA FORMS; ELECTROMAGNETIC RADIATION; ESTERS; HYDROGEN COMPOUNDS; HYDROXY COMPOUNDS; INFORMATION; INTERMEDIATE MASS NUCLEI; IONIZING RADIATIONS; ISOTOPE APPLICATIONS; ISOTOPES; LIPIDS; LIPOTROPIC FACTORS; MAMMALS; NUCLEI; NUMERICAL DATA; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC PHOSPHORUS COMPOUNDS; ORGANS; QUATERNARY COMPOUNDS; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RESPIRATORY SYSTEM; RODENTS; SEPARATION PROCESSES; SOMATIC CELLS; VERTEBRATES; YEARS LIVING RADIOISOTOPES