Published 1990
| Version v1
Report
[18F]-2-FDG as a tool for studying hexokinase kinetics
Description
In the basic research related to the development of radiolabelled glucose analogues or to sugar metabolism, the measurement of hexokinase kinetics is very important. The article of S. J. Gatley et al about the quality control of [18F]-2-FDG preparations using the hexokinase reaction in vitro was the basic idea of the method proposed in this paper dealing with the direct measurement of hexokinase kinetics by the measurement of the activity related to [18F]-2-FDG-6-phosphate. Experimental results indicate that the method is appropriate for hexokinase studies
Additional details
Publishing Information
- Imprint Title
- Eighth international symposium on radiopharmaceutical chemistry. Abstracts: Final report
- Imprint Pagination
- 458 p.
- Journal Page Range
- p. 309.
- Report number
- DOE/ER/60968--1
Conference
- Title
- 8. international symposium on radiopharmaceutical chemistry.
- Dates
- 24-29 Jun 1990.
- Place
- Princeton, NJ (United States).
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 23029684
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Conference, Non-conventional Literature
- Descriptors DEI
- ACTIVITY LEVELS; BIOCHEMICAL REACTION KINETICS; EVALUATION; FLUORODEOXYGLUCOSE; GLUCOSE; HEXOKINASE; HEXOSES; ION EXCHANGE CHROMATOGRAPHY; OXIDOREDUCTASES; PERFORMANCE TESTING; PHOSPHATES; QUALITY CONTROL; RADIOPHARMACEUTICALS; SPECTROPHOTOMETRY
- Descriptors DEC
- ALDEHYDES; ANTIMETABOLITES; CARBOHYDRATES; CHROMATOGRAPHY; CONTROL; DRUGS; ENZYMES; KINETICS; LABELLED COMPOUNDS; MATERIALS; MONOSACCHARIDES; ORGANIC COMPOUNDS; OXYGEN COMPOUNDS; PHOSPHORUS COMPOUNDS; PHOSPHORUS-GROUP TRANSFERASES; PHOSPHOTRANSFERASES; PROTEINS; RADIOACTIVE MATERIALS; REACTION KINETICS; SACCHARIDES; SEPARATION PROCESSES; TESTING; TRANSFERASES
Optional Information
- Secondary number(s)
- CONF-9006363--Absts.