Effect of 188Re on chromosome aberration in human peripheral blood lymphocytes

Human peripheral blood exposed with 188ReO4- at various radioactivities for 54 h was examined to observe the chromosome and chromatin aberrations at metaphases in the mitosis of lymphocytes. The findings indicate that there is an increasing tendency of the aberration yields of both types with increasing 188ReO4- concentration and a dose dependency could be obtained. The aberration yield was best fitted by a quadratic model. Chromatin aberrations, aberration cells and chromosome fragments were fitted into a linear-regression model