Published August 1985 | Version v1
Journal article

18O and secondary 2H kinetic isotope effects confirm the existence of two pathways for acid-catalysed hydrolyses of α-arabinofuranosides

  • 1. Bristol Univ. (UK). Dept. of Organic Chemistry

Description

The 18O kinetic isotope effect on the HClO4-catalysed hydrolysis of 4-nitrophenyl [1-18O]-α-arabinofuranoside (k16/k18) is 1.023 +- 0.003 at 80.0 C; that for isopropyl [1-18O]-α-arabinofuranoside is 0.988 at 30.2 C and the secondary deuterium effect on the hydrolysis of [2-2H]propan-2-yl α-arabinofuranoside (ksub(H)/ ksub(D)) is 0.979. The nitrophenyl glycoside reacts with exocyclic C-O cleavage and the propan-2-yl glycoside by endocyclic C-O cleavage. (author)

Additional details

Publishing Information

Journal Title
J. Chem. Soc. (London), Perkin Trans., II
Journal Issue
no.8
Series
J. Chem. Soc. (London), Perkin Trans., II.
ISSN
0300-9580
CODEN
JCPKB