Published October 2021 | Version v1
Journal article Metadata-only

Dose Escalated Radiation Therapy for Glioblastoma Multiforme: An International Systematic Review and Meta-Analysis of 22 Prospective Trials

Creators

  • 1. Department of Radiation Oncology, Virginia Commonwealth University Health System, Richmond (United States)
  • 2. Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York (United States)
  • 3. Department of Public Health Sciences, Penn State University, Hershey (United States)
  • 4. Department of Radiation Oncology, The James Cancer Hospital at the Ohio State University Wexner Medical Center, Columbus (United States)
  • 5. Department of Radiation Oncology, Penn State Cancer Institute, Hershey (United States)

Description

Limited evidence is available on the utility of dose-escalated radiation therapy (DE-RT) with or without temozolomide (TMZ) versus standard-of-care radiation therapy (SoC-RT) for patients with newly diagnosed glioblastoma multiforme. We performed a systematic review/meta-analysis to compare overall survival (OS) and progression-free survival (PFS) between DE-RT and SoC-RT.

Availability note (English)

Available from http://dx.doi.org/10.1016/j.ijrobp.2021.05.001

Additional details

Identifiers

DOI
10.1016/j.ijrobp.2021.05.001;
PII
S0360301621004880;

Publishing Information

Journal Title
International Journal of Radiation Oncology, Biology and Physics
Journal Volume
111
Journal Issue
2
Journal Page Range
p. 371-384
ISSN
0360-3016
CODEN
IOBPD3

INIS

Country of Publication
United States
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
53124683
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
DIAGNOSIS; GLIOMAS; PATIENTS; RADIATION DOSES; RADIOTHERAPY; REVIEWS
Descriptors DEC
DISEASES; DOCUMENT TYPES; DOSES; MEDICINE; NEOPLASMS; NERVOUS SYSTEM DISEASES; NUCLEAR MEDICINE; RADIOLOGY; THERAPY

Optional Information

Copyright
Copyright (c) 2021 Elsevier Inc. All rights reserved.