Published May 1, 2005 | Version v1
Journal article Metadata-only

Determination of some structural and dispersion characteristics of Perftoran emulsions by the small-angle X-ray scattering

Creators

  • 1. Budker Institute of Nuclear Physics, SB RAS, 630090 Novosibirsk (Russian Federation)
  • 2. Institute of Theoretical and Experimental Biophysics, RAS, 142290 Pushchino, Moscow region (Russian Federation)
  • 3. Vektor State Research Center of Virology and Biotechnology, 630559 Kol'tsovo, Novosibirsk region (Russian Federation)
  • 4. Institute of Cell Biophysics, RAS, 142290 Pushchino, Moscow region (Russian Federation)

Description

By the method of small-angle X-ray scattering, it is shown that preparation Perftoran-the blood substitute with the function of carrying oxygen-contains a huge amount of spherical micellar particles in an abundance, essentially of smaller sizes, than a particle of an emulsion of perfluorochemicals. The distribution function of the form and the size of micellar particles of preparation Perftoran is determined. The assumption, that a number of clinical properties of a preparation is caused by these particles is put forward

Additional details

Identifiers

DOI
10.1016/j.nima.2005.01.139;
PII
S0168-9002(05)00238-X;

Publishing Information

Journal Title
Nuclear Instruments and Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment
Journal Volume
543
Journal Issue
1
Journal Page Range
p. 158-160
ISSN
0168-9002
CODEN
NIMAER

Conference

Title
15. international synchrotron radiation conference
Acronym
SR 2004
Dates
19-23 Jul 2004
Place
Novosibirsk (Russian Federation)

INIS

Country of Publication
Netherlands
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
37033700
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ABUNDANCE; BLOOD SUBSTITUTES; DISTRIBUTION FUNCTIONS; EMULSIONS; OXYGEN; PARTICLES; SMALL ANGLE SCATTERING; SPHERICAL CONFIGURATION; X-RAY DIFFRACTION
Descriptors DEC
COHERENT SCATTERING; COLLOIDS; CONFIGURATION; DIFFRACTION; DISPERSIONS; DRUGS; ELEMENTS; FUNCTIONS; HEMATOLOGIC AGENTS; NONMETALS; SCATTERING

Optional Information

Copyright
Copyright (c) 2005 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.