Published November 2001
| Version v1
Journal article
Modified synthesis of 11-[14C]-clozapine
Description
The reported synthetic pathway of 8-chloro-11-(4-methyl-1-piperazinyl)-11-[14C]-5H-dibenzo[b,e][1,4]diazapine (clozapine) was modified in several steps. The synthetic pathway was shortened by 60% and the total yield was increased from 6% to 23%
Additional details
Identifiers
- PII
- S0969804301001348;
Publishing Information
- Journal Title
- Applied Radiation and Isotopes
- Journal Volume
- 55
- Journal Issue
- 6
- Journal Page Range
- p. 789-791
- ISSN
- 0969-8043
- CODEN
- ARISEF
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- Canada
- INIS RN
- 33027093
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- CARBON 14; LABELLED COMPOUNDS; PSYCHOTROPIC DRUGS; SYNTHESIS; YIELDS
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARBON ISOTOPES; CENTRAL NERVOUS SYSTEM AGENTS; DRUGS; EVEN-EVEN NUCLEI; ISOTOPES; LIGHT NUCLEI; NUCLEI; RADIOISOTOPES; YEARS LIVING RADIOISOTOPES
Optional Information
- Copyright
- Copyright (c) 2001 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.