Analytical design in activation analysis: the role of accuracy and precision

In order to obtain maximum utilization of the technique of activation analysis, a logical and systematic method for the evaluation of alternate analytical procedures is required, especially for analyses requiring a high degree of accuracy and precision. The activation analysis procedure can be separated into the four basic areas: (a) sampling and sample handling; (b) irradiation procedures; (c) radiochemical separations; and (d) detection systems. Each of these areas can then be divided into a number of individual options, each option with its own characteristics, including an uncertainty value. The resulting analytical design results when these options are fused to form a procedure which will adequately meet the requirements. This paper outlines many of the options available in each area and discusses some of their inherent limitations and uncertainties