Published 2018 | Version v1
Journal article Metadata-only

Role of F18 FDOPA positron emission tomography/computed tomography in differentiating the recurrent high-grade gliomas from the recurrent low-grade gliomas

Creators

  • 1. Department of Nuclear Medicine, All India Institutes of Medical Sciences, New Delhi (India)
  • 2. Department of Neurosurgery, All India Institutes of Medical Sciences, New Delhi (India)
  • 3. Department of Pathology, All India Institutes of Medical Sciences, New Delhi (India)
  • 4. Department of Radiation Oncology, All India Institutes of Medical Sciences, New Delhi (India)

Description

The prognosis of the patients with recurrent brain tumors depends upon the grade of the tumor and the proliferation index of the tumor cells. Both these parameters are obtained from the histopathology, which may not always be feasible. With this study, we tried to differentiate the high-grade glioma (HGG) from the low-grade glioma (LGG), using F18 FDOPA positron emission tomography-computed tomography (PET/CT). Furthermore, we tried to establish the relationship between the proliferation index (MiB%) and the semi-quantitative parameters from the PET/CT. PET/CT with F18-FDOPA can distinguish between recurrent HGG and LGG. Further, the proliferation index of the tumor cells correlates with the PET semiquantitative parameters

Availability note (English)

Available from: https://www.ijnm.in/text.asp?2018/33/5/31/245069

Additional details

Identifiers

URL
https://www.ijnm.in/text.asp?2018/33/5/31/245069;

Publishing Information

Journal Title
Indian Journal of Nuclear Medicine
Journal Volume
33
Journal Issue
5,suppl
Journal Page Range
p. S51
ISSN
0972-3919

Conference

Title
50. annual conference of Society of Nuclear Medicine
Acronym
SNMICON 2018
Dates
22-25 Nov 2018
Place
Chandigarh (India)

INIS

Country of Publication
India
Country of Input or Organization
India
INIS RN
52078247
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BIOLOGICAL LOCALIZATION; BRAIN; DIAGNOSIS; DOPA; FLUORINE 18; NEOPLASMS; POSITRON COMPUTED TOMOGRAPHY; RADIOISOTOPE SCANNING; RADIOPHARMACEUTICALS
Descriptors DEC
AMINO ACIDS; AUTONOMIC NERVOUS SYSTEM AGENTS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; HYDROXY ACIDS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; NANOSECONDS LIVING RADIOISOTOPES; NERVOUS SYSTEM; NEUROREGULATORS; NUCLEI; ODD-ODD NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIOACTIVE MATERIALS; RADIOISOTOPES; TOMOGRAPHY