Published April 1977 | Version v1
Journal article Metadata-only

Total body irradiation in non-Hodgkin lymphoma and its effect on bone marrow and peripheral blood

Creators

  • 1. Rotterdams Radio Therapeutisch Instituut (Netherlands)

Description

Patients with non-Hodgkin lymphoma have been treated with total body irradiation (T.B.I.). Very high remission rate is obtained in lymphosarcomas, but response in histiosarcoma is extremely poor. Bone marrow study suggests that marrow depression following T.B.I. is transient and complete recovery occurs provided the bone marrow is not already compromised by previous chemotherapy and radiation therapy. Extreme caution is required when T.B.I. is repeated as this may lead to progressive marrow hypoplasia. (orig.)

Abstract (German)

Patienten mit Nicht-Hodgkin-Lymphomen wurden mit Bestrahlungen des ganzen Koerpers behandelt. Beim Lymphosarkom liess sich eine sehr hohe Remissionsrate erreichen, beim Retikulosarkom aber kaum eine Reaktion feststellen. Die Knochenmarksanalyse erlaubt den Schluss, dass die Schaedigung des Marks nach Ganzkoerperbestrahlung voruebergehend ist und voellige Erholung eintritt, falls das Knochenmark nicht schon durch vorhergehende Chemotherapie oder Strahlenbehandlung gefaehrdet wurde. Groesste Vorsicht ist geboten, wenn die Ganzkoerperbestrahlung wiederholt wird, da dies zur progressiven Hypoplasie des Knochenmarks fuehren kann. (orig.)

Additional details

Publishing Information

Journal Title
Strahlentherapie
Journal Volume
153
Journal Issue
4
Series
Strahlentherapie.
Journal Page Range
232-235

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
8332455
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BLOOD; BONE MARROW; LINEAR ACCELERATORS; LYMPHOMAS; PATIENTS; RADIATION HAZARDS; RADIATION INJURIES; RADIOTHERAPY; WHOLE-BODY IRRADIATION
Descriptors DEC
ACCELERATORS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BIOLOGICAL RADIATION EFFECTS; BODY; BODY FLUIDS; CYCLIC ACCELERATORS; DISEASES; EXTERNAL IRRADIATION; HAZARDS; HEALTH HAZARDS; HEMATOPOIETIC SYSTEM; INJURIES; IRRADIATION; MEDICINE; NEOPLASMS; ORGANS; RADIATION EFFECTS; THERAPY; TISSUES

Optional Information

Notes
4 figs.; 2 tabs.; 2 refs.