Experimental substantiation of the possibility of developing selenium- and iodine-containing pharmaceuticals based on blue-green algae Spirulina platensis
Creators
- 1. Institute of Physics, Georgian Academy of Sciences, Tbilisi (Georgia)
- 2. Frank Laboratory of Neutron Physics, Joint Institute for Nuclear Research, Dubna (Russian Federation)
Description
The great potential of using blue-green algae Spirulina platensis as a matrix for the production of selenium- and iodine-containing pharmaceuticals is shown experimentally. The background levels of 31 major, minor and trace elements (Na, Mg, Al, Cl, K, Ca, Sc, V, Cr, Mn, Fe, Co, Ni (using (n,p)-reaction), As, Br, Zn, Rb, Mo, Ag, Sb, I, Ba, Sm, Tb, Tm, Hf, Ta, W, Au, Hg, Th) in Spirulina platensis biomass were determined by means of epithermal neutron activation analysis. The dependence of selenium and iodine accumulation in spirulina biomass on a nutrient medium loading of the above elements was characterised. To demonstrate the possibilities of determining toxic element intake by spirulina biomass, mercury was selected. The technological parameters for production of iodinated treatment-and-prophylactic pills are developed
Availability note (English)
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Additional details
Publishing Information
- Imprint Pagination
- 14 p.
- Report number
- JINR-D--14-2001-39
INIS
- Country of Publication
- Joint Institute for Nuclear Research (JINR)
- Country of Input or Organization
- Joint Institute for Nuclear Research (JINR)
- INIS RN
- 33000887
- Subject category
- S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- ALGAE; BIOMASS; CONCENTRATION RATIO; DRUGS; ELEMENTS; IBR-2 REACTOR; IODINE; IRRADIATION; MERCURY; NEUTRON ACTIVATION ANALYSIS; NUTRIENTS; SAMPLE PREPARATION; SELENIUM; TRACE AMOUNTS
- Descriptors DEC
- ACTIVATION ANALYSIS; CHEMICAL ANALYSIS; ELEMENTS; ENERGY SOURCES; EPITHERMAL REACTORS; FAST REACTORS; HALOGENS; METALS; NONMETALS; PLANTS; PULSED REACTORS; REACTORS; RENEWABLE ENERGY SOURCES; RESEARCH AND TEST REACTORS; RESEARCH REACTORS; SEMIMETALS
Optional Information
- Notes
- 36 refs., 2 figs., 6 tabs. Submitted to the Journal of Pharmaceutical and Biomedical Analysis