Published May 1984 | Version v1
Journal article

In situ adsorption of bovine submaxillary mucin at the mica/aqueous solution interface

  • 1. Laboratoire de Physico-Chimie des Surfaces et des Membranes, UER Biomedicale, Paris (France)

Description

An in situ adsorption measurement method at the mica/protein solution interface is described. An apparatus especially constructed for this purpose permits direct and continuous measurement of total adsorption (reversible and irreversible) of 14C-labelled proteins. Bovine submaxillary mucin (BSM), extracted from salivary glands, was acetylated with (CH314CO)2O. The results show the increase of BSM adsorbed on mica surfaces with its concentration in solution and adsorption time. Pseudo plateaux are obtained for all concentrations studied, indicating the formation of thick layers. The loosely bound fraction of adsorbed mucin is proportional to the bulk concentration in solution. The amount of BSM adsorbed increases in the neighbourhood of the isoelectric point of BSM (pH 3). (Auth.)

Additional details

Publishing Information

Journal Title
Colloids Surf.
Journal Volume
9
Journal Issue
4
Series
Colloids Surf.
Journal Page Range
297-306
ISSN
0166-6622