Published November 2021 | Version v1
Journal article Metadata-only

18F-FDG PET/CT follow-up of urothelial bladder carcinoma treated with BCG-therapy: A rare case of BCGitis

Creators

  • 1. Centre d'imagerie fonctionnelle, 14, impasse Faye, 33000 Bordeaux (France)
  • 2. Centre hospitalier d'Arcachon, avenue Jean-Hameau, 33260 La Teste-de-Buch (France)
  • 3. CHU de Bordeaux, place Amelie-Raba-Leon, 33000 Bordeaux (France)

Description

We report a diffuse hypermetabolic micronodular lung disease (miliary pattern) in a 61-year-old man who underwent a PET/CT-scan for unexplained asthenia associated with fever symptoms. The patient had a history of urothelial bladder carcinoma treated with transurethral resection and immunotherapy with BCG (Bacille Calmette-Guerin) one year ago. After two month of specific BCG-infection treatment, the post-therapeutic evaluation by 18F-FDG PET/CT show an excellent response of the hypermetabolic pulmonary miliary and confirm the diagnosis of BCGitis. This rare case of 'BCGitis' after BCG-therapy for an urothelial bladder carcinoma highlights the importance to sensitize nuclear physicians on the etiologies of miliary (BCGitis vs. metastases), and on the importance of taking into account the history of the patients thanks to the interrogation. (authors)

Availability note (English)

Available from doi: http://dx.doi.org/10.1016/j.mednuc.2021.05.001

Abstract (French)

Nous presentons le cas d'une miliaire pulmonaire hypermetabolique, decouverte chez un patient de 61 ans, adresse en medecine nucleaire pour une alteration de l'etat general avec asthenie. Le patient avait pour antecedents une neoplasie vesicale traitee par resection trans-uretrale de vessie et BCGtherapie, il y a un, an faisant suspecter une BCGite. Apres deux mois de traitement specifique antituberculeux, l'evaluation therapeutique par TEP-TDM au 18FDG a montre une evolution favorable et a confirme le diagnostic etabli. Ce cas rare de 'BCGite' apres BCGtherapie pour neoplasie vesicale montre l'interet de sensibiliser les medecins nucleaires sur les etiologies des miliaires pulmonaires (BCGite vs metastases) et l'importance de pouvoir interroger les patients pour prendre en compte les antecedents. (auteurs)

Additional details

Additional titles

Original title (English)
TEP-CT au 18FDG dans la prise en charge d'un carcinome urothelial de vessie traite par BCGtherapie: un rare cas de BCGite

Identifiers

DOI
10.1016/j.mednuc.2021.05.001;

Publishing Information

Journal Title
Medecine Nucleaire. Imagerie Fonctionnelle et Metabolique
Journal Volume
45
Journal Issue
no.5-6
Journal Page Range
p. 286-288
ISSN
0928-1258
CODEN
MNIMEX

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
53087683
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BLADDER; CARCINOMAS; DIAGNOSIS; ETIOLOGY; EVALUATION; FEVER; FLUORINE 18; IMMUNOTHERAPY; LUNGS; METASTASES; PATIENTS; POSITRON COMPUTED TOMOGRAPHY
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LIGHT NUCLEI; MEDICINE; NANOSECONDS LIVING RADIOISOTOPES; NEOPLASMS; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIOISOTOPES; RESPIRATORY SYSTEM; SYMPTOMS; THERAPY; TOMOGRAPHY; URINARY TRACT

Optional Information

Notes
9 refs.