Studies of zinc phthalocyanine/magnetic fluid complex as a bifunctional agent for cancer treatment

The present study introduces a new class of material that allows the combined action of photodynamic therapy (PDT) and hyperthermia (HPT) therapies, designed to work in a synergetic way when used in vivo, with an expected enhancement in tumor damaging after minimum drug doses and based on heat dissipation and/or light photosensitization. With this purpose, we have investigated the spectroscopic and photophysical properties of the complex zinc phthalocyanine/magnetic fluid (ZnPC/MF) in homogeneous medium (ethanol). Our findings clearly indicate that the spectroscopic properties of ZnPC as a photosensitizer associated or not with MF present similar behavior working efficiently as a PDT drug