Published 1975 | Version v1
Journal article Metadata-only

The exploration of the sodium pump of red blood cell with 22Na and 42K. II. effect of triamterene

Creators

  • 1. Institut National de la Sante et de la Recherche Medicale (INSERM), Hopital Edouard-Herriot, 69 - Lyon (France)

Description

The study of the effect of triamterene on the movements of sodium and potassium shows: the absence of influence of triamterene on sodium movements, and the decrease of the entry of potassium in red blood cells when the solution contains triamterene. This effect of triamterene might be one of those explaining the potassium-sparing effect of this product

Abstract (French)

L'etude de l'effet du triamterene sur les mouvements du sodium et du potassium du globule rouge a mis en evidence que les coefficients de transport actif du sodium ne sont pas modifies et que le coefficient de transport actif du potassium est significativement diminue (p<0,01), a faible concentration (6x10-6M/l). Cet effet au niveau membranaire du triamterene pourrait etre l'un des facteurs expliquant l'epargne du potassium constatee en clinique sous l'action de cette substance

Additional details

Additional titles

Original title (French)
L'exploration de la pompe a sodium du globule rouge par le

Publishing Information

Journal Title
C. R. Soc. Biol. Fil.
Journal Volume
169
Journal Issue
6
Series
C. R. Soc. Biol. Fil.
Journal Page Range
1543-1545

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
8293348
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ERYTHROCYTES; METABOLISM; PATIENTS; POTASSIUM; POTASSIUM 42; SODIUM; SODIUM 22; TRACER TECHNIQUES
Descriptors DEC
ALKALI METALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; ELEMENTS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOTOPE APPLICATIONS; ISOTOPES; LIGHT NUCLEI; METALS; NUCLEI; ODD-ODD NUCLEI; POTASSIUM ISOTOPES; RADIOISOTOPES; SODIUM ISOTOPES; YEARS LIVING RADIOISOTOPES