Morphological changes in mammary gland cancer of various histastructure after large-dose fractionated preoperative irradiation
Creators
- 1. Khar'kovskij Nauchno-Issledovatel'skij Inst. Meditsinskoj Radiologii (Ukrainian SSR)
Description
The authors studied morphological changes in the tumour of the mammary gland in 16 patients who had undergone preoperative irradiation in the ''Rokus'' unit in large-dose fractionation. In tumours with scirrhous carcinoma of the mammary gland, morphological changes connected with radiation therapy were not observed. In nonscirrhous carcinomas of the mammary gland after preoperative irradiation by large fractions sharp dystrophic changes are revealed in the tumoral cells, growth at the place of the perished cancerous cells of the young connective tissue, and also phenomena of marked sclerosis and hyalinosis in the connective-tissue stroma of the tumour. It has been supposed that using large fractionation for the treatment of scirrhous forms of mammary gland carcinoma is not reasonable
Additional details
Additional titles
- Original title (Russian)
- Морфологические изменения рака молочной железы разной гистоструктуры после крупнофракционированного предоперационного облучения
Publishing Information
- Journal Title
- Med. Radiol.
- Journal Volume
- 23
- Journal Issue
- 7
- Series
- Med. Radiol.
- Journal Page Range
- 42-48
INIS
- Country of Publication
- USSR
- Country of Input or Organization
- USSR
- INIS RN
- 9414561
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; DOSE RATES; FRACTIONATED IRRADIATION; HISTOLOGY; LYMPH NODES; MAMMARY GLANDS; MORPHOLOGICAL CHANGES; NEOPLASMS
- Descriptors DEC
- BIOLOGICAL EFFECTS; BODY; DISEASES; GLANDS; IRRADIATION; LYMPHATIC SYSTEM; ORGANS; RADIATION EFFECTS