Published January 1980 | Version v1
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Chemical problems in neutron capture medical treatment

Creators

  • 1. Tokyo Inst. of Tech. (Japan). Research Lab. of Nuclear Reactor

Description

The natural abundance of B-10, which is useful for neutron capture medical treatment, is only 20 percent, accordingly the enrichment of B-10 is required. The basic anion exchange resin method was designed. By using long columns, the enrichment of B-10 to 96 percent was achieved. The study of boron compounds has been made to obtain a substance with good affinity to tumors. 4-boronophenylalanine (4-bpa) was synthesized, and its character was studied. A new method of the chemical analysis of B-10 was developed. The alkali fusion, methylene blue colorimetric analysis was established. (Kato, T.)

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Additional details

Publishing Information

Imprint Title
Selective thermal neutron capture therapy of cancer cells using their specific functional differentiation
Imprint Pagination
120 p.
Journal Page Range
p. 115-120.
Report number
KURRI-TR--195

INIS

Country of Publication
Japan
Country of Input or Organization
Japan
INIS RN
13658627
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Descriptors DEI
ACTIVATION ANALYSIS; BORON; BORON 10; ISOTOPE SEPARATION; LABELLING; NEUTRON CAPTURE THERAPY; QUANTITATIVE CHEMICAL ANALYSIS; RADIOPHARMACEUTICALS; UPTAKE
Descriptors DEC
BORON ISOTOPES; CHEMICAL ANALYSIS; DRUGS; ELEMENTS; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MEDICINE; NEUTRON THERAPY; NUCLEI; ODD-ODD NUCLEI; RADIOACTIVE MATERIALS; RADIOTHERAPY; SEMIMETALS; SEPARATION PROCESSES; STABLE ISOTOPES; THERAPY