Published October 2000 | Version v1
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Effect of many fold gamma-irradiation with dose 2 Gy on lipid peroxidation in rat liver

  • 1. Inst. biyakhimii, Natsyyanal'naya akadehmiya navuk Belarusi, Grodna, (Belarus)
  • 2. Grodzenski dzyarhawny medytsynski inst., Grodna (Belarus)
  • 3. Grodzenski dzyarhawny agrarny inst., Grodna (Belarus)

Description

We have studied the effect of many fold gamma-irradiation on lipid peroxidation. The experiments were carried out on animal groups: 1, control (without irradiation); 2, irradiation, 2 Gy (0.4 Gy x 5 days). After 1 and 3 days the animals were decapitated and the liver microsomal fraction was isolated by differential centrifugation. The alanine- and aspartate-aminotransferase activities increased for 24 h after irradiation in rat serum. The intensity of NADPH-induced chemo luminescence, diene conjugates and MDA content increased in rat liver microsomes. The stimulation of lipid peroxidation can be one of the pathogenic effects of low-dose gamma-irradiation. (authors)

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Part of:
Proceedings of the international conference devoted to centenary of N.V.Timofeev-Resovskij

Additional details

Additional titles

Original title (Russian)
Влияние многократного гамма облучения в дозе 2 Гр на показатели перекисного окисления в печени крыс

Publishing Information

Imprint Place
Minsk (Belarus)
Imprint Title
Proceedings of the international conference devoted to centenary of N.V.Timofeev-Resovskij
Imprint Pagination
230 p.
Journal Page Range
p. 170-172
Report number
INIS-BY--021

Conference

Title
International conference devoted to centenary of N.V.Timofeev-Resovskij
Original Conference Title
Mezhdunarodnaya konferentsiya, posvyashchennaya 100-letiyu so dnya rozhdeniya N.V.Timofeeva-Resovskogo
Dates
17-18 Oct 2000
Place
Minsk (Belarus)

Optional Information

Notes
1 tab., 7 refs. Imprint:Mezhdunarodnaya konferentsiya, posvyashchennaya 100-letiyu so dnya rozhdeniya N.V.Timofeeva-Resovskogo