Radiotherapy combined with intervention treatment for patients with advanced non-small-cell lung cancers: a randomized study

Objective: To study methods of treatment for advanced non-small-cell lung cancer. Methods: 60 patients with advanced non-small-cell lung cancers whose life expectancy was 3-6 moths were randomly divided into, treatment group and control group with the combination treatment for the former and simple radiotherapy for the latter. The method of radiotherapy was the same in the two groups, with a dose of Dt-60 Gy/30f/6wk. In the combination treatment group, included radiation therapy and interventional treatment with chemotherapeutic drugs. Results: The response rate, mean remission period, median survival time and 1-year survival rate in the combination treatment group were 98.3%, 7.4 months, 11 months and 46.7%, respectively. The outcomes were significantly different from those in the group of patients treated with radiation therapy alone (63.6%, 4.7 months, 6.5 months and 6.7%, respectively, P < 0.01). Conclusions: Radiotherapy combined with interventional treatment can prolong the survival time and improve quality of life in patients with advanced non-small-cell lung cancers