Published June 2019
| Version v1
Journal article
Tumor Control in RG2 Glioma-Bearing Rats: A Comparison Between Proton Minibeam Therapy and Standard Proton Therapy
Creators
- 1. Laboratoire d'Imagerie et Modélisation en Neurobiologie et Cancérologie (IMNC), Centre National de la Recherche Scientifique (CNRS), Universités Paris 11 and Paris 7, Campus d'Orsay, Orsay (France)
- 2. Institut Pasteur, Neuropathologie Experimentale, Paris (France)
Description
Proton minibeam radiation therapy (pMBRT) is a novel radiation therapy approach that exploits the synergies of proton therapy with the gain in normal tissue preservation observed upon irradiation with narrow, spatially fractionated, beams. The net gain in normal tissue sparing that has been shown by pMBRT may lead to the efficient treatment of very radioresistant tumors, which are currently mostly treated palliatively. The aim of this study was to perform an evaluation of the tumor effectiveness of proton minibeam radiation therapy for the treatment of RG2 glioma-bearing rats.
Additional details
Identifiers
- DOI
- 10.1016/j.ijrobp.2019.01.080;
- PII
- S0360301619301713;
Publishing Information
- Journal Title
- International Journal of Radiation Oncology, Biology and Physics
- Journal Volume
- 104
- Journal Issue
- 2
- Journal Page Range
- p. 266-271
- ISSN
- 0360-3016
- CODEN
- IOBPD3
INIS
- Country of Publication
- United States
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 55057210
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- ANIMAL TISSUES; COMPARATIVE EVALUATIONS; GLIOMAS; IRRADIATION; PROTON BEAMS; RADIOSENSITIVITY; RADIOTHERAPY; RATS
- Descriptors DEC
- ANIMALS; BEAMS; BODY; DISEASES; EVALUATION; MAMMALS; MEDICINE; NEOPLASMS; NERVOUS SYSTEM DISEASES; NUCLEAR MEDICINE; NUCLEON BEAMS; PARTICLE BEAMS; RADIOLOGY; RODENTS; SENSITIVITY; THERAPY; VERTEBRATES
Optional Information
- Copyright
- Copyright (c) 2019 Elsevier Inc. All rights reserved.