Evaluation of abdominal digestive tumors with 18F-FDG coincidence imaging

Objective: To evaluate the clinical usefulness of 18F-fluorodeoxyglucose (FDG) coincidence imaging in detecting suspected abdominal digestive tumors or recurrent cancer. Methods: 51 patients with suspected abdominal digestive malignant tumors or recurrent cancer underwent 18F-FDG coincidence imaging using GE HAWKEYE coincidence SPECT at 40-60 min after the intravenous injection of 259-298 MBq 18F-FDG. The acquired data were reconstructed using iterative algorithm, attenuation-corrected using X ray and fused using CT. The images were interpreted visually by nuclear physician with double blindness. The results were also compared and assessed with the clinical diagnosis, histological examination CT and MRI findings. Results: In all patients with suspected abdominal digestive malignant tumors, the sensitivity, specificity and accuracy of 18F-FDG coincidence imaging was 94.1%, 76.5% and 88.2% respectively. And in the patients with colorectal recurrent cancer, the sensitivity, specificity and accuracy were 94.1%, 83.3% and 91.3% respectively. Conclusion: 18F-FDG coincidence imaging had highly sensitivity and accuracy in diagnosis of abdominal digestive malignant tumor or recurrent cancer