Published 2019 | Version v1
Journal article Metadata-only

Prognostic significance of pretreatment 68Ga-dotanoc positron emission tomography/ computed tomography in paediatric neuroblastoma

Creators

  • 1. Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh (India)
  • 2. Department of Paediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh (India)

Description

Neuroblastoma, a neural crest cell derived tumor, is a common malignancy in childhood. It is a heterogeneous disease with several factors known to affect treatment and survival outcomes. Expression of somatostatin receptors (SSTRs) in neuroblastoma allows positron emission tomography/computed tomography (PET/CT) imaging with 68Ga labelled somatostatin analogues and detection of metastatic burden. The present study was conducted to evaluate the prognostic role of 68Ga - DOTANOC PET/CT in paediatric neuroblastoma and compare it with other known risk factors. 68Ga - DOTANOC PET/CT assisted in metastatic work up and risk stratification of patients with neuroblastoma, thereby making it a non-invasive and cost-effective biomarker in this setting. It also has therapeutic implications with regard to selection of patients for Peptide Receptor Radionuclide Therapy

Additional details

Publishing Information

Journal Title
Indian Journal of Nuclear Medicine
Journal Volume
34
Journal Issue
5,suppl.1
Journal Page Range
p. 26
ISSN
0972-3919

Conference

Title
51. annual conference of the society of nuclear medicine, India - abstracts
Acronym
SNMICON-2019
Dates
12-15 Dec 2019
Place
Mumbai (India)

INIS

Country of Publication
India
Country of Input or Organization
India
INIS RN
52109847
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference
Descriptors DEI
CT-GUIDED RADIOTHERAPY; GALLIUM 68; METASTASES; NEOPLASMS; POSITRON COMPUTED TOMOGRAPHY; TUMOR CELLS
Descriptors DEC
ANIMAL CELLS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; EMISSION COMPUTED TOMOGRAPHY; GALLIUM ISOTOPES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOTOPES; MEDICINE; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; RADIOISOTOPES; RADIOLOGY; RADIOTHERAPY; THERAPY; TOMOGRAPHY