Effect of x irradiation or chelate administration on transport of plutonium across rat intestine

Experiments carried out after abdominal x irradiation indicated increased permeability of the gastrointestinal tract to 238Pu at doses of 800 rad or above. Measurement of movement of 238Pu from the isolated duodenum also indicated increased 238Pu transport after 800 to 1500 rad. By the same technique, we were able to show that the increased urinary excretion of 239Pu measured after gavage with 239Pu-DTPA by Baxter and Sullivan (Health Phys. 22: 785, 1972) was indeed due to increased transport across the FI tract. Bile, however, had no measurable effect on 238Pu transport