99mTc generator - the maintenance of high elution efficiency

Several protecting procedures were applied to ensure good operating performances of the universal 99mTc generators based on fission produced 99Mo. These procedures include the modifications of the absorbent. Instead of 1 g of pure Al2O3 the adsorption of 99Mo is carried out on the multicomponent adsorbent containing the mixture of either Al2O3 + SiO2 or Al2O3 · Cu2+ + SiO2. The protection by drying should ensure that the columns contain minimum of moisture during the growth period of 99mTc. It was found experimentally that the best results are obtained when the ratio of alumina in the mixture was 15 ± 5 (wt.%) and content of copper 365 μg Cu2+/column. The comparison of efficiency and applicability of the used protecting procedures is also given. (author)