Sample handling and chemical procedures for efficacious trace analysis of urine by neutron activation analysis

Important for the determination of trace elements, ions, or compounds in urine by chemical neutron activation analysis is the optimization of sample handling, preirradiation chemistry, and radioassay procedures necessary for viable analysis. Each element, because of its natural abundance in the earth's crust and, hence, its potential for reagent and environmental contamination, requires specific procedures for storage, handling, and preirradiation chemistry. Radioassay techniques for radionuclides vary depending on their half-lives and decay characteristics. Described in this paper are optimized procedures for aluminum and selenium. While 28Al (T1/2 = 2.24 min) and 77mSe(T1/2 = 17.4s) have short half-lives, their gamma-ray spectra are quite different. Aluminum-28 decays by a 1779-keV gamma and 77mSe by a 162-keV gamma. Unlike selenium, aluminum is a ubiquitous element in the environment requiring special handling to minimize contamination in all phases of its analytical determination