Published May 2005 | Version v1
Journal article

Modelling magnetic carrier particle targeting in the tumor microvasculature for cancer treatment

  • 1. School of Biological Sciences, University of Aberdeen, Cruickshank Building, St. Machar Drive, Aberdeen (United Kingdom)

Description

Magnetic drug targeting of tumors situated in the cavity of the human body is difficult because the magnetic gradients decrease rapidly with the distance from the magnets. Here computer simulations are used to investigate different techniques to focus small MPs within the microvasculature of tumors. Non-invasive methods were found to have range <15 cm whilst minimal invasive methods could be applied specifically to small tumors (<18 mm)

Additional details

Identifiers

DOI
10.1016/j.jmmm.2005.01.081;
PII
S0304-8853(05)00146-0;

Publishing Information

Journal Title
Journal of Magnetism and Magnetic Materials
Journal Volume
293
Journal Issue
1
Journal Page Range
p. 639-646
ISSN
0304-8853
CODEN
JMMMDC

Conference

Title
5. International conference on scientific and clinical applications of magnetic carriers
Dates
20-22 May 2004
Place
Lyon (France)

INIS

Country of Publication
Netherlands
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
37029358
Subject category
S60: APPLIED LIFE SCIENCES;
Resource subtype / Literary indicator
Conference
Descriptors DEI
CARRIERS; COMPUTERIZED SIMULATION; DRUGS; MAGNETS; NEOPLASMS; THERAPEUTIC USES
Descriptors DEC
DISEASES; EQUIPMENT; SIMULATION; USES

Optional Information

Copyright
Copyright (c) 2005 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.