Published May 11, 2005 | Version v1
Journal article

A simple hydrophobicity-based score for profiling protein structures

  • 1. Departamento de Fisica e Matematica, FFCLRP Universidade de Sao Paulo, Avenida Bandeirantes 3900. CEP 14040-901 Ribeirao Preto, SP (Brazil)
  • 2. Department of Physics, Michigan Technological University, Houghton, MI 49931-1295 (United States)

Description

We propose a simple measure that allows the profiling of protein configurations. It is based on calculation of a restricted radius of gyration evaluated only between the centroids of hydrophobic residues and measures the formation and compactness of the hydrophobic core. Some preliminary results for applications of the new score in generalized-ensemble simulations are presented

Availability note (English)

Available online at http://stacks.iop.org/0953-8984/17/S1595/cm5_18_015.pdf or at the Web site for the Journal of Physics. Condensed Matter (ISSN 1361-648X) http://www.iop.org/

Additional details

Publishing Information

Journal Title
Journal of Physics. Condensed Matter
Journal Volume
17
Journal Issue
18
Journal Page Range
p. S1595-S1606
ISSN
0953-8984
CODEN
JCOMEL

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
36104361
Subject category
S75: CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY; S60: APPLIED LIFE SCIENCES;
Descriptors DEI
COMPUTERIZED SIMULATION; CONFIGURATION; MOLECULAR STRUCTURE; PROTEIN STRUCTURE; PROTEINS; RESIDUES
Descriptors DEC
ORGANIC COMPOUNDS; SIMULATION