Published 1987 | Version v1
Book Metadata-only

Mutagenous effect of tritium on genital cells of mammals

Creators

  • 1. Nauchno-Issledovatel'skij Inst. Radiatsionnoj Gigieny, Leningrad (USSR)

Description

Genetic effect of tritium on mice males depending on titanium chemical composition (THO,3H-glucose, 3H-thymidine) and comparing with γ-radiation effect has been studied. Dependence of dominant lethal mutations (DLM) frequency and reciprocal translocations (RT) on the absorbed dose in testes cells and on the time after irradiation has been studied. Absence of differences in chromosomal abberation frequencies caused by THO and 3H-glucose and detected according to DLM criteria in differentiating cells and RT in spermatogonia is shown. As far as the value of both effects does not exceed the expected one at the given dose, 3H-glucose and tritium oxide do not obviously possess nucleotropic properties

Additional details

Additional titles

Original title (Russian)
Мутагенное действие трития на половые клетки млекопитающих

Publishing Information

Publisher
Nauka.
Imprint Place
Moscow (USSR)
Imprint Title
Radiation mutagenesis and its role in evolution and selection
Journal Page Range
p. 66-73.

INIS

Country of Publication
USSR
Country of Input or Organization
USSR
INIS RN
19067234
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
CHEMICAL COMPOSITION; DOMINANT MUTATIONS; EMBRYOS; GAMMA RADIATION; GENETIC RADIATION EFFECTS; LETHAL MUTATIONS; MALES; MICE; SPERMATOCYTES; SPERMATOGONIA; TESTES; TIME DEPENDENCE; TRITIUM COMPOUNDS
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; ELECTROMAGNETIC RADIATION; GENETIC EFFECTS; GERM CELLS; GONADS; HYDROGEN COMPOUNDS; IONIZING RADIATIONS; MALE GENITALS; MAMMALS; MUTATIONS; ORGANS; RADIATION EFFECTS; RADIATIONS; RODENTS; VERTEBRATES

Optional Information

Notes
15 refs.; 4 figs. Imprint:Radiatsionnyj mutagenez i ego rol' v ehvolyutsii i selektsii.