Published September 1974 | Version v1
Journal article

Radioimmunoassay of plasma elastase

  • 1. Hahnemann Medical Coll., Philadelphia

Description

A radioimmunoassay system was developed for the measurement of canine elastase. The method is able to measure elastase in plasma in concentrations ranging from 0.1 to 2.0 μg/ml. No cross-reactivity was found with trypsin or chymo-trypsin. The elastase levels in canine plasma were measured during experimental pancreatitis. Within 15 min after the induction of pancreatitis, the elastase levels as measured by radioimmunoassay increased to about 2.5 times their control levels. They remained above the control levels through-out the course of the experiment. On the other hand the elastolytic activity decreased after pancreatectomy.

Additional details

Additional titles

Augmented title (English)
"1"2"5I tracer technique

Identifiers

Publishing Information

Journal Title
Experimental Biology and Medicine
Journal Volume
146
Journal Issue
4
Series
Proc. Soc. Exp. Biol. Med.
Journal Page Range
997-1002
ISSN
1535-3702

Optional Information

Notes
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