Published 1975
| Version v1
Report
Carbon-13 NMR study of [Phe4,Tyr8] angiotension-II
- 1. National Research Council of Canada, Ottawa
Description
The 13C nuclear magnetic resonance (NMR) spectra and spinlattice relaxation times (T1) are reported for [Phe4,Tyr8]-angiotensin-II in D2O at 67.9 MHz. Comparison between these data and those obtained for [Ile5]-angiotensin-II show that the mobilities of the aromatic rings in angiotensin-II are affected both by the positions the rings occupy in the sequence as well as by the nature of the ring substituents. Moving a phenylalanine residue from position 8 to position 4 reduces its mobility to that of tyrosine at position 4. However, when tyrosine occupies position 8, it does not exhibit the same degree of freedom as does phenylalanine at this position
Additional details
Publishing Information
- Imprint Title
- Proceedings of the second international conference on stable isotopes
- Imprint Pagination
- p. 456-461.
- Report number
- CONF-751027--
Conference
- Title
- 2. international conference on stable isotopes.
- Dates
- 20 Oct 1975.
- Place
- Oak Brook, Illinois, USA.
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 8314893
- Subject category
- S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- ANGIOTENSIN; AROMATICS; BIOCHEMICAL REACTION KINETICS; CARBON 13; CHEMICAL SHIFT; ISOTOPE EFFECTS; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE; PHENYLALANINE; SPECTRA; SPIN-LATTICE RELAXATION; TYROSINE
- Descriptors DEC
- AMINO ACIDS; CARBON ISOTOPES; CARBOXYLIC ACIDS; DRUGS; EVEN-ODD NUCLEI; GLOBULINS; HYDROXY ACIDS; ISOTOPES; KINETICS; LIGHT NUCLEI; MAGNETIC RESONANCE; NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; PROTEINS; REACTION KINETICS; RELAXATION; RESONANCE; STABLE ISOTOPES; SYMPATHOMIMETICS