Hypereosinophilic syndrome with hepatic involvement : US, CT and MRI findings

To evaluate the findings of US, CT and MRI in the hepatic involvement of hypereosinophilic syndrome. We reviewed imaging findings of hypereosinophilic syndrome with hepatic involvement in nine patients. Imaging studies were US(n=9), conventional CT(CCT, n=6), dynamic incremental CT(DICT, n=3), and MRI with conventional spin-echo sequence(MRI-CSE, n=3). For DICT, we obtained images of the early arterial phase(n=1), portal venous phase(n=3) and the late venous phase(n=3). T1WI were obtained with 600-700 msec/13-17msec(TR/TE) and T2WI were obtained with 1850-2300 msec/80-90 msec(n=3). Gadolinium-enhanced T1WI were also obtained(n=2). US showed multiple hypoechoic or isoechoic nodules(7/9) and appeared normal(2/9). CCT showed multiple hypodense nodules(5/6) and appeared normal(1/6). DICT showed patchy, multiple hypodense nodules and showed hepatic nodules during the portal venous phase only(3/3). MRI-CSE showed one to several focal high-signal nodules on T2WI and subtle low-signal nodules on T1WI(2/3), and showed several subtle high-signal lesions on Gd-enhanced T1WI(1/2) and appeared normal on T1, T2WI(1/3). Hepatic involvement of hypereosinophilic syndrome showed varied imaging findings on US, CT and MRI