Spatially Fractionated Radiotherapy: Dosimetric and Clinical Report

Lattice is a three-dimensional technical development of the two-dimensional grid technology, which forms high-dose ⁱslands amid a ^sea of lower dose. When compared to grid, lattice offers enhanced dose distribution and organs-at-risk (OAR) sparing, which may be useful for big or deep-seated cancers. In this study, we used a Halcyon 2.0 (6MV) linear accelerator to treat the palliative cases with lattice radiation using volumetric modulated arc treatment (VMAT). Bulky tumors were treated with lattice radiation with a high dose per fraction in this study, with the vertices receiving the specified dose and the region between the vertices being spared. As it was a task for physicists to design a lattice radiation considering the vertices and periphery regions and to achieve the OARs according to the dose constraint protocol, the VMAT plan was well realized using optimization and computation