Published December 1976 | Version v1
Journal article

A 51Chromium release assay for phagocytic killing of Candida albicans

  • 1. Saint Mary's Hospital Medical School, London (UK)

Description

Intracellular killing of Candida albicans was measured by a chromium release technique. Appropriate conditions were equal numbers of polymorphonuclear leucocytes (PMN) and 51Chromium labelled C. albicans (106/ml), fresh plasma at a final concentration of 2.5%, incubated at 37degC for 60 min. Using normal PMNs, 35-71% of releasable chromium was liberated into the supernatant under these conditions. This assay is easy to perform, requires a small amount of blood and offers an objective measurement of intracellular killing of C. albicans

Additional details

Identifiers

Publishing Information

Journal Title
Journal of Immunological Methods
Journal Volume
13
Journal Issue
3-4
Series
J. Immunol. Methods.
Journal Page Range
227-233
ISSN
0022-1759

Optional Information

Notes
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