Published December 23, 1982
| Version v1
Journal article
125I-labelled cobalamin derivative compatible with intrinsic factor
Description
A 125I-labelled derivative of cobalamin (vitamin B12) is described which is compatible with intrinsic factor in binding assays. The derivative, [125I]cyanocobalamin-d-iodohistamide, can be readily prepared with a specific activity of 1400 Ci/g. Used as a substitute for [57Co]cyanocobalamin in binding assays, the new derivative can reduce counting times and decrease costs in such assays. (Auth.)
Additional details
Publishing Information
- Journal Title
- Clin. Chim. Acta
- Journal Volume
- 126
- Journal Issue
- 3
- Series
- Clin. Chim. Acta.
- Journal Page Range
- 315-322
- ISSN
- 0009-8981
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- Netherlands
- INIS RN
- 14745326
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- CHEMICAL BONDS; CHEMICAL PREPARATION; COBALT 57; INTRINSIC FACTOR; IODINATION; IODINE COMPLEXES; IODINE 125; LABELLING; RADIOACTIVITY; VITAMIN B-12
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; CARBOHYDRATES; CHEMICAL REACTIONS; COBALT ISOTOPES; COMPLEXES; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; HALOGENATION; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; MUCOPROTEINS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; POLYSACCHARIDES; PROTEINS; RADIOISOTOPES; SACCHARIDES; SYNTHESIS; VITAMIN B GROUP; VITAMINS