Diffusion tensor imaging parameters in differentiation recurrent breast cancer from post-operative changes in patients with breast-conserving surgery

Highlights: • Recurrence have significantly higher FA values (P = 0.003, 0.02) than in post-operative changes. • Recurrence have significantly lower MD (P = 0.001, 0.001) than post-operative changes. • Strong positive correlation of MD (r = 0.86) and FA (r = 0.73) of both observers. - Abstract: Aim of the workTo investigate mean diffusivity (MD) and fractional anisotropy (FA) measured by diffusion tensor imaging (DTI) as complementary tools to differentiate recurrent breast cancer from post-operative changes in patients with breast-conserving surgery (BCS).