Published March 2001
| Version v1
Journal article
Extensive white-matter changes in case of adult polyglucosan body disease
- 1. Dept. of Neurology, Inselspital, Berne (Switzerland)
- 2. Dept. of Neuropathology, Univ. of Berne (Switzerland)
- 3. Dept. of Neuroradiology, Univ. of Berne (Switzerland)
Description
Extensive white matter signal changes were observed on T2-weighted images of a 49-year-old man. He presented with a slowly progressive gait disorder, and finally developed severe dementia. Extensive metabolic and infectious investigations failed to disclose the underlying cause during life. Autopsy revealed adult polyglucosan body disease. We discuss MRI findings likely to permit this diagnosis if combined with clinical findings and nerve or skin biopsy. (orig.)
Additional details
Publishing Information
- Journal Title
- Neuroradiology
- Journal Volume
- 43
- Journal Issue
- 3
- Journal Page Range
- p. 234-236
- ISSN
- 0028-3940
- CODEN
- NRDYAB
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 32013923
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BEHAVIOR; BRAIN; COMPUTERIZED TOMOGRAPHY; CONGENITAL DISEASES; MENTAL DISORDERS; MOTION; NMR IMAGING
- Descriptors DEC
- BODY; CENTRAL NERVOUS SYSTEM; DIAGNOSTIC TECHNIQUES; DISEASES; NERVOUS SYSTEM; ORGANS; TOMOGRAPHY
Optional Information
- Notes
- With 3 figs., 9 refs.