Published June 2010 | Version v1
Report Metadata-only

Preclinical comparison study of biological assessment of carbon ion beams at Gunma university of heavy ion medical center

Creators

  • 1. Gunma Univ., Graduate School of Medicine, Maebashi, Gunma (Japan)

Description

The purpose of this study was to assess biologic effect of carbon beam of Gunma University compared with that of Heavy Ion Medical Accelerator in Chiba (HIMAC) before clinical use in vitro and in vivo. The aim of this study is to assess quality assurance of biological effect of heavy ion therapy facility. In vitro study, HSG-C5 cells (human salivary gland cancer) relative biological effectiveness (RBE) values calculate from survival curves at the dose that reduces cell survival to 10% (D10). Cell cycle distribution after carbon irradiation was analyzed by flowcytometry on 6 cm spread-out Bragg peak (SOBP). And we will try to confirm new brief assessment methods using another biological endopoint of RBE values. (author)

Part of:
2009 annual report of the research project with heavy ions at NIRS-HIMAC

Additional details

Identifiers

URL
http://id.nii.ac.jp/1657/00073735/;

Publishing Information

Imprint Title
2009 annual report of the research project with heavy ions at NIRS-Himac
Imprint Pagination
338 p.
Journal Page Range
p. 36-37
Report number
NIRS-M--234

INIS

Country of Publication
Japan
Country of Input or Organization
Japan
INIS RN
53066940
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Non-conventional Literature
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; BRAGG CURVE; CARBON 12 BEAMS; CARBON IONS; CELL CYCLE; DOSE-RESPONSE RELATIONSHIPS; HEAVY IONS; HIMAC ACCELERATOR; IN VITRO; LET; RBE; SURVIVAL CURVES; TUMOR CELLS; X RADIATION
Descriptors DEC
ACCELERATORS; ANIMAL CELLS; BEAMS; BIOLOGICAL EFFECTS; CHARGED PARTICLES; CYCLIC ACCELERATORS; DIAGRAMS; ELECTROMAGNETIC RADIATION; ENERGY TRANSFER; HEAVY ION ACCELERATORS; INFORMATION; ION BEAMS; IONIZING RADIATIONS; IONS; RADIATION EFFECTS; RADIATIONS; SYNCHROTRONS

Optional Information

Notes
This record replaces 45037347
Secondary number(s)
HIMAC--134