A kit formulation for preparation of [111In]In-DTPA-folate, a folate-receptor-targeted radiopharmaceutical

A kit formulation has been developed for convenient, routine compounding of 111In-labeled In(III)-DTPA-Folate, an investigational radiopharmaceutical for targeting tumor-associated folate receptors. The kit consists of the DTPA-Folate conjugate in sodium citrate solution, from which [111In]In-DTPA-Folate can be rapidly and reliably compounded by the addition of aqueous [111In]In(III)-chloride