Effect of hyperthermia and ionizing radiation used alone or in combination on tumor metastases
Creators
- 1. Akademiya Meditsinskikh Nauk SSSR, Obninsk (USSR). Nauchno-Issledovatel'skij Inst. Meditsinskoj Radiologii
Description
The paper is devoted to a study of the effect of hyperthermia and irradiation used alone or in combination on the frequency and intensity of metastasizing of Walker carcinoma in rats, sarcoma-37 and 2 types (LLC and LLC-1) of Lewis lung carcinoma in mice. The frequency and intensity of metastasis depend not only on tumor type but also on a transplantation site. Metastasizing of tumor cells transplanted under the leg skin, occurs after a tumor reaches the volume of 25 mm3. Local hyperthermia (40-45 deg C) and irradiation used alone or in combination, do not change the frequency and intensity of metastasis. However if a rise of body temperature is noted on local hyperthermia, larger tumor nodes appear in the lungs without evidence of an increase in the number of metastases
Additional details
Additional titles
- Original title (Russian)
- Влияние раздельного или сочетанного действия гипертермии и ионизирующего излучения на метастазирование опухолей
Publishing Information
- Journal Title
- Meditsinskaya Radiologiya
- Journal Volume
- 33
- Journal Issue
- 12
- Series
- Med. Radiol.
- Journal Page Range
- 34-40
- ISSN
- 0025-8334
- CODEN
- MERAA
INIS
- Country of Publication
- Russian Federation
- Country of Input or Organization
- USSR
- INIS RN
- 20052125
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL LOCALIZATION; EXPERIMENTAL NEOPLASMS; HYPERTHERMIA; IONIZING RADIATIONS; LIFE SPAN; METASTASES; MICE; RATS; SIZE
- Descriptors DEC
- ANIMALS; BODY TEMPERATURE; DISEASES; MAMMALS; NEOPLASMS; RADIATIONS; RODENTS; VERTEBRATES