Efficiency of S-heterylmodified cysteamine in at acute radiation syndrome in in rats

The radioprotective efficiency of the S- (6-ethoxy-2- methylquinolin-4-yl)-cysteamine in modeling of acute radiation syndrome in rats were studied. The radioprotective effect resulted in reduction of lethality, prevention of radiation-induced apoptosis, preservation of the total number of myelocaryocytes and colony-forming mesenchymal stromal cells of the bone marrow and reduction of radiation cytopenia. The high radioprotective efficiency of the S-(6-ethoxy-2-methylquinolin-4-yl)-cysteamine in protection of the hemopoietic system in acute radiation syndrome was established.