Study on the correlationship among serum ACA, hs-CRP and Hcy levels in patients with cerebral infarction
Creators
- 1. department of Nuclear Medicine Nanjing First Hospital Affiliated to Nanjing Medical Univ., Nanjing (China)
- 2. Department of Neurology, Nanjing First Hospital Affiliated to Nanjing Medical Univ., Nanjing (China)
Description
Objective: To study the changes of and correlationship among serum anti-cardiolipin antibody (ACA), hs-CRP and Hcy levels in patients with cerebral infarction. Methods: Serum ACA (with ELISA), hs-CRP(with RIA) and Hcy(with CLIA) levels were measured in 210 patients with cerebral infarction and 30 controls. Results: The serum ACA, hs-CRP and Hcy contents in the patients with cerebral infarction were significantly higher than those in the controls. Serum hs-CRP and Hcy levels in the patients were mutually positively correlated (r=0.714). Serum ACA levels in the patients were also positively correlated with serum hs-CRP levels(r=0.893) and Hcy levels(r=0.597). Conclusion: High serum ACA, hs-CRP and Hcy levels were independent risk factors in the development of cerebral infarction. Combined determination of serum ACA, hs-CRP and Hcy levels was helpful for early diagnosis in patients with cerebral infarction. (authors)
Additional details
Publishing Information
- Journal Title
- Journal of Radioimmunology
- Journal Volume
- 22
- Journal Issue
- 5
- Journal Page Range
- p. 440-442
- ISSN
- 1008-9810
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 42057378
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- ANTIBODIES; BRAIN; CARDIOLIPIN; CONCENTRATION RATIO; CORRELATIONS; DIAGNOSIS; ENZYME IMMUNOASSAY; GLOBULINS; HAZARDS; HOMOCYSTEINE; ISCHEMIA; PATIENTS; RADIOIMMUNOASSAY
- Descriptors DEC
- AMINO ACIDS; ANEMIAS; BIOASSAY; BODY; CARBOXYLIC ACIDS; CARDIOVASCULAR DISEASES; CENTRAL NERVOUS SYSTEM; DIAGNOSTIC TECHNIQUES; DIMENSIONLESS NUMBERS; DISEASES; ESTERS; HEMIC DISEASES; IMMUNOASSAY; ISOTOPE APPLICATIONS; LIPIDS; NERVOUS SYSTEM; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC PHOSPHORUS COMPOUNDS; ORGANS; PHOSPHOLIPIDS; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; SYMPTOMS; TRACER TECHNIQUES; VASCULAR DISEASES
Optional Information
- Notes
- 1 tab., 7 refs.