Published December 1992 | Version v1
Journal article Metadata-only

Alterations of mitochondrial DNA: a method for the detection of irradiated beef liver

Creators

  • 1. Faculte de Pharmacie, Lab. de Chimie Analytique, 67400 Illkirch-Graffenstaden (France)
  • 2. Centre National de la Recherche Scientifique (CNRS), 67 - Strasbourg (France)
  • 3. Faculte de Faculte de Pharmacie, Lab. de Chimie Analytique, 67400 Illkirch-Graffenstaden (France)

Description

The study of the radio degradation of DNA is one of a number of phenomena being investigated to develop methods for identifying irradiated foods. The specific behaviour under radiation of the mitochondrial DNA from beef liver gives the possibility of detecting if the product has been irradiated or not. An identification method could finally be developed. The appraisal of the mitochondrial supercoiled DNA fraction constitutes an unambiguous detection test for beef liver irradiation. A total of 120 different samples were irradiated at 5 different doses. The dose limit of detection is lower than 2 kGy. No effects due to storage conditions were observed. (Author)

Additional details

Publishing Information

Journal Title
Radiation Physics and Chemistry
Journal Volume
40
Journal Issue
6
Journal Page Range
p. 485-488.
ISSN
0146-5724
CODEN
RPCHDM

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
24032578
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S60: APPLIED LIFE SCIENCES;
Descriptors DEI
CHEMICAL RADIATION EFFECTS; DNA; ELECTRON BEAMS; MEAT; MITOCHONDRIA; POST-IRRADIATION EXAMINATION; RADIATION DOSES; SENSITIVITY; STRAND BREAKS; TEMPERATURE RANGE 0273-0400 K
Descriptors DEC
BEAMS; CELL CONSTITUENTS; FOOD; LEPTON BEAMS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; PARTICLE BEAMS; RADIATION EFFECTS; TEMPERATURE RANGE

Optional Information

Contract/Grant/Project number
Grants 51.88.02; 88.G.1019; 90.H.0616