Published January 1988
| Version v1
Journal article
Radiation induced heart disease in hypertensive rats
Description
Spontaneously hypertensive Wistar rats were given single doses of X rays to their heart. Irradiation decreased the blood pressure before any myocardial radiation damage was apparent. Male rats, which were more hypertensive than female rats, had a shorter survival time after local heart irradiation than female rats. Antihypertensive treatment with hydralazine did not increase the survival time. It is considered that myocardial hypertrophy is the cause of the increased susceptibility of spontaneously hypertensive rats to local heart irradiation
Additional details
Publishing Information
- Journal Title
- Int. J. Radiat. Oncol., Biol. Phys.
- Journal Volume
- 14
- Journal Issue
- 1
- Series
- Int. J. Radiat. Oncol., Biol. Phys.
- Journal Page Range
- 109-114
- ISSN
- 0360-3016
- CODEN
- IOBPD
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 19049892
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- ACUTE IRRADIATION; BIOLOGICAL RADIATION EFFECTS; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; DOSE-RESPONSE RELATIONSHIPS; HEART; HYPERTENSION; MYOCARDIUM; RADIATION EFFECTS; RATS; SEX DEPENDENCE; X RADIATION
- Descriptors DEC
- ACUTE EXPOSURE; ANIMALS; BIOLOGICAL EFFECTS; BODY; CARDIOVASCULAR SYSTEM; DISEASES; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; IRRADIATION; MAMMALS; MUSCLES; ORGANS; RADIATIONS; RODENTS; SYMPTOMS; VASCULAR DISEASES; VERTEBRATES