Effects of ultraviolet and visible light of the transplantability of fibrosarcoma in mice

Tumour cells from solid fibrosarcoma of Swiss mice were irradiated with ultraviolet radiation and with combined UV and visible light irradiation. These cells were subcutaneously transplanted in mice. One group with non-irradiated cells was used as control. Non-irradiated tumour cells showed positive growth in most of the animals, UV-irradiated group showed gross inhibition of tumour growth, and UV plus visible light irradiation cells showed response comparable to control, non-irradiated group. UV-irradiated group showed diminished protein staining of nuclear chromatins. Results are discussed. (M.G.B.)