Antibacterial graphene oxide coatings on polymer substrate

Highlights: • Antibacterial GO coatings on modified silicone rubber surface were prepared. • The coatings presented edge-free morphology, differing from GO nanosheets precursor. • The flat and featureless coatings showed obvious antibacterial activity. • Oxidative stress mechanism was considered the main factor of antibacterial activity. Graphene oxide (GO) was thought to be a promising antibacterial material. In this work, graphene oxide coatings on polymer substrate were prepared and the antibacterial activity against E. coli and S. aureus was investigated. It was demonstrated that the coatings exhibited stronger antibacterial activity against E. coli with thin membrane than S. aureus with thick membrane. Take into consideration the fact that the coatings presented smooth, sharp edges-free morphology and bonded parallelly to substrate, which was in mark contrast with their precursor GO nanosheets, oxidative stress mechanism was considered the main factor of antibacterial activity. The coatings, which are easy to recycle and have no inhalation risk, provide an alternative for application in antibacterial medical instruments.