Sublimation enthalpies of 9 substituted acetanilides at 298 K estimated by solution calorimetry approach

Highlights: • Solution enthalpies of 10 acetanilides in acetonitrile were measured at 298 K. • Sublimation enthalpies of 9 acetanilide derivatives were calculated using the solution calorimetry approach. • Obtained data are in good agreement with the results of the direct experiments. - Abstract: In this work a solution calorimetry approach was applied for determination of the sublimation enthalpies of 9 substituted acetanilides. The solution enthalpies of acetanilide and 9 its derivatives in acetonitrile were measured and solvation enthalpies were calculated by a group-additivity scheme. Additivity of solvation enthalpy due to influence of the substituent on the acidity of the proton of NHCOCH₃-group and OH-group was checked with the use of IR-spectroscopy. The sublimation enthalpies obtained from the solution calorimetry approach were compared to the available literature data. In most cases convergence within the limits of experimental uncertainty was demonstrated.