Published April 3, 2006 | Version v1
Journal article

cDNA microarray screening in food safety

  • 1. From the Laboratory of Molecular Medicine and DNA Microarray and Genetics Facility, Dorothy M. Davis Heart and Lung Research Institute, Department of Surgery, The Ohio State University Medical Center, Columbus, OH 43210 (United States)

Description

The cDNA microarray technology and related bioinformatics tools presents a wide range of novel application opportunities. The technology may be productively applied to address food safety. In this mini-review article, we present an update highlighting the late breaking discoveries that demonstrate the vitality of cDNA microarray technology as a tool to analyze food safety with reference to microbial pathogens and genetically modified foods. In order to bring the microarray technology to mainstream food safety, it is important to develop robust user-friendly tools that may be applied in a field setting. In addition, there needs to be a standardized process for regulatory agencies to interpret and act upon microarray-based data. The cDNA microarray approach is an emergent technology in diagnostics. Its values lie in being able to provide complimentary molecular insight when employed in addition to traditional tests for food safety, as part of a more comprehensive battery of tests

Additional details

Identifiers

DOI
10.1016/j.tox.2005.12.025;
PII
S0300-483X(06)00046-1;

Publishing Information

Journal Title
Toxicology
Journal Volume
221
Journal Issue
1
Journal Page Range
p. 128-133
ISSN
0300-483X
CODEN
TXCYAC

INIS

Country of Publication
Ireland
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
37080127
Subject category
S60: APPLIED LIFE SCIENCES;
Descriptors DEI
DIAGNOSIS; DIET; FOOD; MICROARRAY TECHNOLOGY; NUTRITION; PATHOGENS; REVIEWS; SAFETY; TOXINS
Descriptors DEC
ANTIGENS; BIOTECHNOLOGY; DOCUMENT TYPES; HAZARDOUS MATERIALS; MATERIALS; TOXIC MATERIALS

Optional Information

Copyright
Copyright (c) 2006 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.